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14-3-3 PROTEINS
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DeCS
Descritor
Inglês
:
14-3-3 Proteins
Descritor
Espanhol
:
Proteinas 14-3-3
Descritor
Português
:
Proteínas 14-3-3
Categoria:
D12.644.360.024.313
D12.776.157.057.126
D12.776.476.024.406
Definição
Inglês
:
A large
family
of signal-transducing adaptor
proteins
present in wide variety of eukaryotes. They are
PHOSPHOSERINE
and
PHOSPHOTHREONINE
binding
proteins
involved in important cellular processes including
SIGNAL TRANSDUCTION
; CELL-CYCLE
control
;
APOPTOSIS
; and cellular
stress
responses.
14-3-3 proteins
function by interacting with other signal-transducing
proteins
and effecting changes in their enzymatic activity and subcellular localization. The name 14-3-3 derives from numerical designations used in the original fractionation patterns of the
proteins.
Nota Histórica
Inglês
:
2005(1981)
Qualificadores Permitidos
Inglês
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Número do Registro:
38740
Identificador Único:
D048948
Ocorrência na BVS
:
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